This section of the forum is dedicated to discussions on various surgical techniques for facial rejuvenation, including fat transfer/fat grafting, browlift, blepharoplasty (cosmetic eyelid surgery), facelift, etc. Also, this category includes questions on hand rejuvenation via fat grafting. (Of note, Dr. Lam does not perform body rejuvenation except for hand fat grafting)
5FU in my opinion will only bring down a fat graft if it is firm and fibrotic, i.e., has surrounding scar tissue in it. If it is just too much fat or a lump, it is better to excise it IMHO. once the fibrosis is managed, it should be permanently corrected. however, it might take a few rounds. the major risk of 5FU is temporary to permanent skin color changes if injected too superficially into the dermis. it should be injected deeper into the area of fibrosis to be safe. i don't mix it with steroid unless i am targeting a keloid. steroids are too risky but for keloids, 5FU alone will fail. (obviously, we are not talking about keloids here.) hope that helps. best, sml
Samuel M. Lam, M.D., F.A.C.S.
Diplomate, American Board of Facial Plastic & Reconstructive Surgery
Diplomate, American Board of Otolaryngology Head & Neck Surgery
Diplomate, American Board of Hair Restoration Surgery